5-HTP stands for L-5-hydroxytryptophan, which comes from the amino acid tryptophan found in many proteins and the seeds of an African plant known as Griffonia simplicifolia. 5-HTP is primarily used to support mood through its ability to increase serotonin ? the neurotransmitter associated with happiness ? and the neurohormone melatonin. It can also be used for several conditions where serotonin is believed to play an important role. 5-HTP has been compared to various antidepressants and has been found to be as effective and faster-acting with fewer side effects. Since serotonin and melatonin are involved in regulating the sleep/wake cycle, 5-HTP can enhance sleep quality. Additionally, research supports a role for 5-HTP in reducing headaches and the symptoms of fibromyalgia. Several clinical trials with 5-HTP have confirmed significant improvements in symptoms associated with fibromyalgia including pain, morning stiffness, nervousness, and fatigue. Ultimately, those who suffer with mood imbalances such as low mood and anxiety, or from migraines, fibromyalgia or sleep disorders may benefit from taking 5-HTP.